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Home » Archive » 2015

TDK conference 2015

The effect of significantly higher and accelerated music upon the behaviour of mice.
Rácz Nóra - year 4
SzIU, Faculty of Veterinary Science, Institute for Animal Breeding, Nutrition and Laboratory Animal Science
Supervisors: Sándor György Fekete DVM, Gabriella Korsós DVM

Abstract:

The significance of acoustic stimuli plays a different role in the life of laboratory rodents. The too loud noise and/or vibration of the animal facilities may be a stressor for the animals. The well-chose background music may counteract these effects. Besides the general effects, music may have specific influence on the animals. In the present experiments "rodentised" music has been used by increasing the pitches to the healing range of mice (1kHz-85,5kHz). During the first trial twenty adult male (SPF, CD1) mice were used and continuous video recording was made. The mice were placed by pair in individually ventillated cage (IVC). Two type of music were applied, Mozart and Bach but ten times faster and five octaves higher. First the basal ethogram has been taken thereafter the Mozart and with break the Bach. The following behaviour elements were registered: walking, sniffing, self-grooming and grooming the cage mate, rest, rearing, digging in the bedding and eating. Owing to both types of musical stimuli, the rearing get significantly more frequent and the running time decreased. Although the nervous grooming and resting time increased, but owing to the great standard variation the differencies are not significative. In the second trial twelve male BALB/c mice were investigated using TiBeSplit open-field equipment, linked with screen and software. On Day 1 the human, on Day 2 the rodentized versions were used, and on Day 3 the same procedure was repeated in silence. The registered parameters were as follows: distance of movement (m), resting (% of time), local movement (% of time), large movement (% of time), crossing the center (occasion), spontaneous change of movement (occasion) and time spent around the walls. The lenght of distance, the local and large movement, as well as the number of spontaneous changes of direction significantly decreased. On the contrary the resting time and the lenght of time spent at the wall significantly increased under the influence of faster music. Taken together, the effect of rodentized music differ that of the human version, and the genotype plays also a role. The basicly calm CD1 mice got more active (more rearing, less running) and the more actie BALB/c animals became less nervous owing to the musical stimuli.



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