Students' Research Circle    
 
 
2022
2021
2020
2019
2018
» 2017
The conference
Veterinary Session
Veterinary Jury
Sponsors
Awards-list
HSF
Call for papers
2016
2015
2014
2013
2012
2011
2010
2009
2008
2007
2006
2005
2004
2003
2002
Home » Archive » 2017

TDK conference 2017

Heritability analysis of equine grass sickness
Varga Márta - year 4
University of Veterinary Medicine, Department Animal Breeding, Nutrition and Laboratory Animal Science
Supervisor: Dr. Boglárka Vincze

Abstract:

Equine grass sickness is described as an often fatal, degenerative polineuropathy in equine species. Despite the large number of studies dealt with the possible causatives (nutritional factors, toxic agents, soil contamination, bacterial/fungal/viral infections, weather factors, Clostridium botulinum toxaemia, etc.) of EGS in the last decades, the causative agent, as well as the pathomechanism is still unknown.

The aim of our study was to assess the possible heritability of the disease based on pedigree analysis methods in the studied population. The 95% confidence interval of prevalence of the disease has been estimated with the Stern-method. The independence of sires and the genetic predisposition of the disease have been tested with the Fisher’s exact test. All analyses have been performed in R statistical program.

Our study revealed the increased occurrence of the disease among the descendants of particular sires; in addition, the prevalence of the disease cumulated in particular parent-offspring connections in the studied population. According to our results, a possible genetic background is likely to occur in case of equine grass sickness.



List of lectures