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Home » Archive » 2014

TDK conference 2014

3D reconstruction and volumetric measurement of the canine ventricles with MRI
Benedek Bianka Zsuzsanna - year 5
SZIU Faculty of Veterinary Science, Department of Anatomy and Histology
Supervisor: dr. László Zoltán Reinitz

Abstract:

The mean cerebrospinal fluid (CSF) volume of the dog ventricles has not yet been scientifically measured. Human data is based on post-mortem tests, and the results show huge divergence from the few in-vivo results.

There is a clinical need of a well-defined mean CSF volume for the early diagnose of hydrocephalus in both human and veterinary medicine, and also for myelography which is still commonly used in the veterinary medicine. Our goal was to define a measuring or estimation method which can be used in the everyday practice for determining the mean CSF volume.

In our study, we performed T2 balanced spin echo MRI on 12 asymptomatic, vaccinated, male mongrel dogs of the age between 3 and 5 years. We used 3DSlicer imaging software for the 3D ventricular reconstructions and measurements.

Total ventricular volume was found to be 0,97-2,94 ml. The lateral ventricle was 62,12 ± 11,7%, the third ventricle was 17,58 ± 4,92 %, the aqueduct of Sylvius was 4,85 ± 1,57 %, and the fourth ventricle was 15,45 ± 6,61% of the total volume. Measures were verified by two validation methods showing 99,96% and 99,8 ± 3,1% accuracy.

Although we could not find direct connection between the ventricular CSF volume and the body measurements, the differences between the right and left ventricular volumes can support the diagnose of hydrocephalus, despite the small sample size.

The developed method is proven to be capable to measure the CSF with high accuracy therefore it can be used in similar researches in the future.



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